Chris Knight is the Senior Director of Health Economics at RTI Health Solutions (Manchester, UK).
Knight has over 18 years of experience in operational research, including the management of projects using health economics, Markov modelling, simulation modelling and statistical modelling techniques to explore disease progression and the impact of treatment across a range of areas, with a particular interest in orphan diseases including osteosarcoma, mucopolysaccharidosis and Castleman’s disease.
Knight has also developed innovative mathematical models – including Markov state transition models and Monte-Carlo simulation models – at both cohort and individual patient levels.
Prior to joining RTI Health Solutions, Knight was responsible for leading a team producing rapid review health technology appraisal reports for the National Institute for Health and Care Excellence (NICE; London, UK) and for applying cost-effective modelling to pharmaceutical companies and service planning for the NHS. Knight also served as an operational research analyst at the School of Health and Related Research at the University of Sheffield (UK).
Knight is on the Editorial Advisory Board of the Journal of Comparative Effectiveness Research and also serves as a peer reviewer for the European Journal of Health Economics, Medical Decision Making, Pharmacoeconomics, Clinical Therapeutics and Haemophilia.